Annual Conference

Dates 26 February (Fri.), 27 February (Sat.), 2010 Chairs Masakazu Toi (Chief) (President, OOTR)
Louis Chow (Executive Director, OOTR)
Nadir Arber
Theme Oncological Biomarkers and Clinical Applications
Venue The Westin Miyako Hotel Kyoto
Sponsorships Kyoto Prefecture, Kyoto City, The Kyoto Shimbun Co.,Ltd,
Ministry of Education, Culture, Sports, Science and Technology
'Raising Proficient Oncologists' (Kyoto University)
The main topics will be - Prognosis and Predictive factors for therapeutic gain / Biomarkers for therapy personalisation.
(Antiangiogenesis therapy, Modulation of intracellular signals etc.)

Programme

Day1: Friday 26th February 2010 (Registration 7:30 A.M.)

Time Session# Session title Topics Moderators Speakers Co-
organiser
8:15 Opening Remarks OOTR 2010 conference agenda and topics Chow LWC Toi M  
8:30 Session1 Intracellular and extracellular signals PAK1-driven oncologic pathways Kumar R
Sabe H		 Kumar R Novartis
Pharma
K.K.
9:00 Significance of epithelial mesenchymal transition (EMT) in cancer malignancy Saya H
9:30 Integrin activation and E-cadherin inactivation by the Arf6 pathway specific to breast cancer invasion and metastasis Sabe H
10:00 Coffee Break
10:30 Session2 Oncological markers MGMT status of human glioma cells and response to temozolomide, irradiation and nelfinavir Ohno S Sminia P  
11:00 Identification and characterisation of tumor suppressor genes on 3p in esophageal squamous cell carcinoma Guan XY
11:30 Discussion   Kumar R
Sabe H
Ohno S		  
12:00 Lunch
13:00 Poster Discussion
13:30 Session3 Challenge of oncological biomarkers Biomarker application in colorectal cancer diagnosis and treatment Chow LWC
Arber N		 Arber N Pfizer
Japan Inc.
14:00 Discovery and clinical application of a lung cancer oncogene, EML4-ALK Mano H
14:30 Novel strategies to overcome trastuzumab resisteance in HER2 positive breast cancer Krop IE
15:00 Discussion   Chow LWC
Arber N		  
15:30 Break
15:45 Seminar1 New molecular targeting treatment and biomarkers Molecularly targeted therapy for breast cancer Aapro M Rugo HS CHUGAI PHARMA-CEUTICAL CO.,LTD
16:15 Predictive factors in rectal and colon cancer: Toward personalised therapy Nakamura S Gasparini G

Gala Dinner *

Venue: The Westin Miyako Hotel Kyoto 2F Room "Yamashiro-no-ma"
Time: 19:00
         Enrollment starts at 18:30
         Door open at 18:50
Dress Code: Casual

*Online registration is required

Day2: Saturday 27th February 2010 (Registration 8:00 A.M.)

Time Session# Session title Topics Moderators Speakers Co-
organiser
8:30 Morning Seminar Apoptosis Apoptosis and its regulation by chemical ligands Kuroi K Umezawa K  
9:00 Seminar1 New molecular targeting treatment and biomarkers Molecular biomarkers for bevacizumab Iwata H Scherer SJ CHUGAI PHARMA-CEUTICAL CO.,LTD
9:30 Coffee Break
10:00 Session4 Personalisation of antiangiogenesis therapy Pharmacogenetic approach to predict clinical response of chemotherapy in advanced colorectal cancer patients Rugo HS
Ueno T		 Kanai M  
10:30 Metronomic chemotherapy: Recent preclinical and clinical advances Kerbel RS
11:00 Circulating tumor cells for individualised cancer treatment Lu J
11:30 Discussion   Rugo HS
Ueno T		  
12:00 Lunch
13:20 Awards presentation for poster presenters  
13:30 Session5 Optimisation of antiangiogenesis therapy Local and systemic impacts of antiangiogenic drugs on cancer patients Cao Y
Bertolini F		 Cao Y TAIHO PHARMA-CEUTICAL CO.,LTD
14:00 Vasohibin-1in human breast carcinoma: A potential negative feedback reglulator of angiogenesis and a marker for neovascularisation Sasano H
14:30 Circulating endothelial cells as biomarkers in medical oncology Bertolini F
15:00 Break
15:15 Seminar2 Antiangiogenesis therapy The role of angiogenesis inhibitors in the treatment of breast cancer Inamoto T Winer EP  
15:45 Discussion   Toi M
Winer EP		    
16:30 Closing Remarks     Chow LWC  

The above is subject to change